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ObjectiveThis study explored the risk factors for infant hospitalization in urban and peri-urban/rural Tanzania.MethodsWe conducted a prospective cohort study examining predictors of hospitalization during the first year of life among infants enrolled at birth in a large randomized controlled trial of neonatal vitamin A supplementation conducted in urban Dar es Salaam (n = 11,895) and peri-urban/rural Morogoro region (n = 20,104) in Tanzania. Demographic, socioeconomic, environmental and birth outcome predictors of hospitalization were assessed using proportional hazard models.ResultsThe rate of hospitalization was highest during the neonatal period in both Dar es Salaam (102/10,000 neonatal-months) and Morogoro region (78/10,000 neonatal-months). Hospitalization declined with increased age and was lowest for infants 6-12 months of age in both Dar es Salaam (11/10,000 infant-months) and Morogoro region (16/10,000 infant-months). In both Dar es Salaam and Morogoro region, older maternal age, male sex, low birth weight and being small for gestational age were significant predictors of higher risk of hospitalization (p ConclusionsThis study determined high rates of neonatal hospitalization in Tanzania. Interventions to increase birth size may decrease risk of hospitalization. Equity in access to hospitals for poor rural families in Tanzania requires attention.

Original publication

DOI

10.1093/tropej/fmv030

Type

Journal

Journal of tropical pediatrics

Publication Date

10/2015

Volume

61

Pages

317 - 328

Addresses

Harvard School of Public Health, Department of Global Health and Population, 655 Huntington Avenue, Boston, MA 02115, USA briegleb.harvard@gmail.com.

Keywords

Humans, Pregnancy Complications, Infectious, Vitamin A Deficiency, Birth Weight, Vitamin A, Vitamins, Hospitalization, Morbidity, Proportional Hazards Models, Prospective Studies, Double-Blind Method, Maternal Age, Sex Factors, Pregnancy, Pregnancy, Multiple, Socioeconomic Factors, Dietary Supplements, Adult, Infant, Infant, Newborn, Rural Population, Urban Population, Tanzania, Female, Male