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Hydroxychloroquine could still prevent COVID-19 and save tens of thousands of lives around the world, say leading scientific researchers. While it doesn’t work in treatment of hospitalised patients, it could still prevent infections. However, fraudulent data, unjustified extrapolation and exaggerated safety concerns together with intense politicisation and negative publicity may stop COPCOV, the only large, global clinical trial testing hydroxychloroquine in COVID-19 prevention, from ever finding out.
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MORU 2020. Photographer: Supa-at (Ice) Asarath.
Clinical Trials Support Group (CTSG)
The Clinical Trials Support Group (CTSG) supports investigators conducting research for the MORU Tropical Health Network and in collaboration with MORU sister units in Vietnam and Kenya – an international endeavour both in Thailand and across Southeast Asia and Africa
Clinical Therapeutics Unit (CTU)
The Clinical Therapeutics Unit (CTU) conducts clinical studies on the treatment of uncomplicated malaria and analyses and models pathological responses in malaria, G6PD deficiency, vivax relapse and anti-infective drug pharmacometric and pharmacodynamics data.
Epidemiology
MORU Epidemiology studies the factors that contribute to the risk of different diseases and how to reduce those risks. The research portfolio includes clinical studies, descriptive epidemiology, and statistical and mathematical modelling of human diseases in South and Southeast Asia and Africa with a focus on malaria, dengue, novel pathogens and environmental health.
Bioethics & Engagement
Paying attention to the public and communities is essential to make our programmes ethical and trustworthy, to maximise their success and impact.
Mathematical and Economic Modelling (MAEMOD)
The Mathematical and Economic MODelling (MAEMOD) Department’s main research focus is mathematical and economic models supporting investigations into the transmission, control and elimination of tropical diseases.
Clinical Pharmacology
Established in 2003 to meet a need for accurate, sensitive antimalarial drug measurements in the biological fluids of clinical trials patients, MORU’s Department of Clinical Pharmacology is now one of the world’s leading laboratories for antimalarial drug pharmacology.
Microbiology
Opened in 1986, the Microbiology Department conducts research on: melioidosis, scrub typhus and other rickettsial infections; antimicrobial resistance; leptospirosis; the epidemiology of infectious diseases; sepsis and severe sepsis; the evaluation of diagnostic tests; and the immunology and cell biology of infectious diseases.
Malaria & Critical illness
The aim of the Malaria & Critical Illness Department at MORU is to improve health through research that addresses threats arising from malaria for billions of people who live in malaria endemic zones around the globe. Our research focuses on the diagnosis, pathophysiology, treatment including the raising issue of drug resistance, prevention and elimination of malaria