Luigi Pisani
Postdoc Clinical Researcher
Currently a postdoc clinical researcher at MORU in Bangkok, Thailand where he co-leads the MORU Critical Care Asia-Africa Network, Luigi is an intensivist-anaesthesiologist trained in Italy, with a passion for critical care in low-resource settings. The Critical Care Asia-Africa Network is a Wellcome Flagship Innovations project, setting up in 15 countries in South Asia and Africa a network for critical care data-driven research and quality improvement using a cloud-based registry, with Luigi closely involved in its work in Africa (Kenya, Uganda, Sierra Leone, Ethiopia, Mozambique, South Africa) and Bangladesh.
Luigi has been at MORU since 2017, when he undertook his PhD at Amsterdam University and MORU in 2017-20, with a focus on mechanical ventilation, pulmonary ultrasound and monitoring in low- and middle-income countries, with studies involving South Asian countries and Sierra Leone.
Luigi’s research focus is studies blending physiology, clinical research and epidemiology aiming to improve care for critically ill patients in Africa and Asia.
At MORU, he also leads two MOTIP-funded projects focused on validating and extending the use of lung ultrasound in African children with critical illness: i. the lung ultrasound in severe malaria study (2018-2022): and ii. the Innovative health technologies for low-resource settings: lung ultrasound-implemented differential diagnosis of acute respiratory distress in African children (2022 to date). In addition, Luigi closely collaborates with OUCRU in Vietnam working on machine learning applications in lung ultrasound.
Luigi co-supervises several PhD students from Africa, Europe and Asia in the UK (Oxford University), Netherlands (University of Amsterdam) and Brazil (D’Or Institute in Rio de Janeiro). He also heads critical care operational research for Doctors with Africa CUAMM, Italy’s largest and oldest health NGO, and is a member of the ICU benchmarking platform LOGIC, the European Society of Intensive Care Medicine (ESICM), and the Italian Intensive Care Quality Improvement Group (GIVITI).
A busy clinician, Luigi works as a consultant intensivist in the ICU of Miulli Regional Hospital in Puglia, Italy.
Key publications
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Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies.
Journal article
Pisani L. et al, (2022), The Lancet. Global health, 10, e227 - e235
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Lung Ultrasound Prediction Model for Acute Respiratory Distress Syndrome: A Multicenter Prospective Observational Study.
Journal article
Smit MR. et al, (2023), Am J Respir Crit Care Med
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Performance evaluation of a multinational data platform for critical care in Asia.
Journal article
Collaboration for Research, Implementation and Training in Critical Care - Asia Investigators None. et al, (2021), Wellcome open research, 6
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Flow Index: a novel, non-invasive, continuous, quantitative method to evaluate patient inspiratory effort during pressure support ventilation.
Journal article
Albani F. et al, (2021), Critical care (London, England), 25
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Epidemiological Characteristics, Ventilator Management, and Clinical Outcome in Patients Receiving Invasive Ventilation in Intensive Care Units from 10 Asian Middle-Income Countries (PRoVENT-iMiC): An International, Multicenter, Prospective Study
Journal article
Pisani L. et al, (2021), The American Journal of Tropical Medicine and Hygiene
Recent publications
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The Significance of Sizes: Which Matters Most?
Journal article
Pisani L. and Schultz MJ., (2024), Chest, 165, 233 - 235
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Impact and burden of sickle cell disease in critically ill obstetric patients in a high dependency unit in Sierra Leone-a registry based evaluation.
Journal article
Mortara M. et al, (2023), BMC pregnancy and childbirth, 23
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Validation of New Quantitative Lung Ultrasound Protocol and Comparison With Lung Ultrasound Score in Patients With COVID-19.
Journal article
Heldeweg MLA. et al, (2023), Chest
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Lung Ultrasound to Determine the Effect of Lower vs. Higher PEEP on Lung Aeration in Patients without ARDS-A Substudy of a Randomized Clinical Trial.
Journal article
Zimatore C. et al, (2023), Diagnostics (Basel, Switzerland), 13
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Thoracic UltrasONOgraphy Reporting: The TUONO Consensus.
Journal article
Calamai I. et al, (2023), Diagnostics (Basel), 13